People

Jeffrey Bluestone, PhD

A.W. and Mary Margaret Clausen Distinguished Professor 

Director, Hormone Research Institute
Diabetes Center

Jeffrey Bluestone, PhD, is the A.W. and Mary Margaret Clausen Distinguished Professor of Metabolism and Endocrinology and is the Director of the Hormone Research Institute in the Diabetes Center. His research over the past 25 years has focused on understanding the basic processes that control T cell activation and immune tolerance in autoimmunity and organ transplantation.

Jennifer Bridge, PhD

Postdoctoral Scholar
Diabetes Center

Shen Dong, PhD

Postdoctoral Scholar
Diabetes Center

Daniel Goodman, PhD

Postdoctoral Scholar
(co-advised by Alex Marson and Kole Roybal)
Diabetes Center

Immune receptors are surprisingly modular and can be mutated and composed to rewire cellular inputs and outputs, as showcased by the success of cell-based genetic therapies like Chimeric Antigen Receptor T-cell (CAR-T) therapy. My work involves high-throughput pooled screening of millions of different synthetic receptors. A better understanding of the relationship between receptor sequence, signaling outcome, and cellular phenotype will lead to next-generation cell-based genetic therapies which manipulate the immune system to combat a variety of diseases.

Angela Lares, MS, BS

Technician
Diabetes Center

James Lee, MD

Clinical Fellow
Medicine

I am a hematology/oncology fellow with significant research experience in adoptive T cell therapy using chimeric antigen receptors (CARs). My current focus is on the design of next generation CARs for more effective therapy in the setting of a tolerant/suppressive tumor microenvironment in solid malignancies.

Michael Lee

Specialist
Flow Cytometry & Monoclonal Antibody Core Director

Weihong Liu, PhD

Specialist
Diabetes Center

Sadaf Mehdizadeh

Staff Research Associate

Lien Thi Nguyen

Lab Assistant
Diabetes Center

Amy Putnam

Specialist
Diabetes Center

Jason Quiros, BS

Technician
Diabetes Center

Caroline Raffin, PhD

Postdoctoral Scholar
Diabetes Center

Leonardo Ramos Ferreira, PhD

Postdoctoral Scholar
(co-advised by Qizhi Tang)
Department of Surgery

Cell-based gene therapies offer unprecedented promise for medicine. One day, it may be possible to cure degenerative diseases consisting of the loss of specialized cellular functions. However, several hurdles must be surpassed to establish cell transplantation therapies. A major one is rejection by the recipient's immune system. This challenge is particularly prominent for autoimmune disorders, such as type 1 diabetes and multiple sclerosis, where the immune system mediates the destruction of self-tissues.

Wendy Rosenthal

Technician
Diabetes Center

Eleonora Trotta, PhD

Postdoctoral Scholar
Diabetes Center

Vivian Tucker

Executive Assistant
Diabetes Center

Frederic Van Gool, PhD

Assistant Professor
Diabetes Center

Linda Vo, PhD

Postdoctoral Scholar
Diabetes Center

Arabella Young, PhD

Postdoctoral Scholar
Diabetes Center